Assay Detail
Functional
CHEMBL893665
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Growth inhibition of HT29 cells by sulforhodamine assay
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HT-29 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthetic chalcones, flavanones, and flavones as antitumoral agents: biological evaluation and structure-activity relationships.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 4.34 | 4.86 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL397027 | — | — | 1 | 4.86 |
| CHEMBL241861 | — | — | 1 | 4.35 |
| CHEMBL105496 | 4-METHOXY CHALCONE | — | 1 | 4.27 |
| CHEMBL7976 | CHALCONE | — | 1 | 4.16 |
| CHEMBL32147 | 2'-HYDROXYCHALCONE | — | 1 | 4.07 |
| CHEMBL294099 | — | — | 1 | - |
| CHEMBL244458 | — | — | 1 | - |
| CHEMBL89988 | — | — | 1 | - |
| CHEMBL241862 | — | — | 1 | - |
| CHEMBL389328 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL397027 | — | IC50 | = | 13800.0 | nM | 4.86 |
| CHEMBL241861 | — | IC50 | = | 45000.0 | nM | 4.35 |
| CHEMBL105496 | 4-METHOXY CHALCONE | IC50 | = | 54000.0 | nM | 4.27 |
| CHEMBL7976 | CHALCONE | IC50 | = | 70000.0 | nM | 4.16 |
| CHEMBL32147 | 2'-HYDROXYCHALCONE | IC50 | = | 85000.0 | nM | 4.07 |
| CHEMBL294099 | — | IC50 | - | — | - | |
| CHEMBL244458 | — | IC50 | - | — | - | |
| CHEMBL89988 | — | IC50 | - | — | - | |
| CHEMBL241862 | — | IC50 | - | — | - | |
| CHEMBL389328 | — | IC50 | - | — | - |