Assay Detail
Binding
CHEMBL894011
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Binding affinity to calf thymus DNA
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bos taurus |
| Confidence | 3 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Spectroscopic studies of DNA binding modes of cation-substituted anthrapyrazoles derived from emodin.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 4.55 | 5.17 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL289277 | EMODIN | — | 1 | 5.17 |
| CHEMBL244745 | — | — | 1 | 4.60 |
| CHEMBL243249 | — | — | 1 | 4.26 |
| CHEMBL244950 | — | — | 1 | 4.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL289277 | EMODIN | Ki | = | 6800.0 | nM | 5.17 |
| CHEMBL244745 | — | Ki | = | 25300.0 | nM | 4.60 |
| CHEMBL243249 | — | Ki | = | 55200.0 | nM | 4.26 |
| CHEMBL244950 | — | Ki | = | 69800.0 | nM | 4.16 |