Assay Detail
Functional
CHEMBL894012
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Cytotoxicity against mouse B16 cells
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | B16 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Spectroscopic studies of DNA binding modes of cation-substituted anthrapyrazoles derived from emodin.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.05 | 5.44 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL243249 | — | — | 1 | 5.44 |
| CHEMBL244745 | — | — | 1 | 5.00 |
| CHEMBL244950 | — | — | 1 | 4.70 |
| CHEMBL289277 | EMODIN | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL243249 | — | IC50 | = | 3600.0 | nM | 5.44 |
| CHEMBL244745 | — | IC50 | = | 10100.0 | nM | 5.00 |
| CHEMBL244950 | — | IC50 | = | 20100.0 | nM | 4.70 |
| CHEMBL289277 | EMODIN | IC50 | > | 100000.0 | nM | - |