Assay Detail
Functional
CHEMBL894013
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human HepG2 cells
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HepG2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Spectroscopic studies of DNA binding modes of cation-substituted anthrapyrazoles derived from emodin.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.78 | 5.31 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL243249 | — | — | 1 | 5.31 |
| CHEMBL244950 | — | — | 1 | 5.14 |
| CHEMBL244745 | — | — | 1 | 4.42 |
| CHEMBL289277 | EMODIN | — | 1 | 4.26 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL243249 | — | IC50 | = | 4900.0 | nM | 5.31 |
| CHEMBL244950 | — | IC50 | = | 7200.0 | nM | 5.14 |
| CHEMBL244745 | — | IC50 | = | 37600.0 | nM | 4.42 |
| CHEMBL289277 | EMODIN | IC50 | = | 55100.0 | nM | 4.26 |