Assay Detail
Functional
CHEMBL894331
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Inhibition of CXCL8-induced cell migration in L1.2 cells expressing Ile43Val CXCR1 mutant by chemotaxis assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | L1.2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Design of noncompetitive interleukin-8 inhibitors acting on CXCR1 and CXCR2.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.10 | 7.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL191413 | REPARIXIN | 3.0 | 1 | 7.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL191413 | REPARIXIN | IC50 | = | 80.0 | nM | 7.10 |