Assay Detail
Binding
CHEMBL894391
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Activity at human LXRalpha by Gal4 transactivation assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
N-Acylthiadiazolines, a new class of liver X receptor agonists with selectivity for LXRbeta.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 6.62 | 7.18 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL59030 | — | — | 1 | 7.18 |
| CHEMBL427697 | — | — | 1 | 6.46 |
| CHEMBL387997 | — | — | 1 | 6.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL59030 | — | EC50 | = | 66.0 | nM | 7.18 |
| CHEMBL427697 | — | EC50 | = | 346.0 | nM | 6.46 |
| CHEMBL387997 | — | EC50 | = | 608.0 | nM | 6.22 |