Assay Detail
Binding
CHEMBL894470
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Displacement of [3H]CP-55940 from CB2 receptor in mouse spleen membrane
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Tissue | Spleen |
| Subcellular | Membrane |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
C1'-cycloalkyl side chain pharmacophore in tetrahydrocannabinols.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 11 | 7.98 | 8.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL389118 | — | — | 1 | 8.92 |
| CHEMBL231465 | — | — | 1 | 8.77 |
| CHEMBL231466 | — | — | 1 | 8.74 |
| CHEMBL231368 | — | — | 1 | 8.38 |
| CHEMBL231565 | — | — | 1 | 8.31 |
| CHEMBL231268 | — | — | 1 | 7.94 |
| CHEMBL67464 | — | — | 1 | 7.68 |
| CHEMBL231367 | — | — | 1 | 7.63 |
| CHEMBL231369 | — | — | 1 | 7.34 |
| CHEMBL390404 | — | — | 1 | 7.28 |
| CHEMBL231464 | — | — | 1 | 6.84 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL389118 | — | Ki | = | 1.2 | nM | 8.92 |
| CHEMBL231465 | — | Ki | = | 1.7 | nM | 8.77 |
| CHEMBL231466 | — | Ki | = | 1.8 | nM | 8.74 |
| CHEMBL231368 | — | Ki | = | 4.2 | nM | 8.38 |
| CHEMBL231565 | — | Ki | = | 4.9 | nM | 8.31 |
| CHEMBL231268 | — | Ki | = | 11.5 | nM | 7.94 |
| CHEMBL67464 | — | Ki | = | 20.8 | nM | 7.68 |
| CHEMBL231367 | — | Ki | = | 23.5 | nM | 7.63 |
| CHEMBL231369 | — | Ki | = | 45.5 | nM | 7.34 |
| CHEMBL390404 | — | Ki | = | 52.3 | nM | 7.28 |
| CHEMBL231464 | — | Ki | = | 143.3 | nM | 6.84 |