Assay Detail
Binding
CHEMBL895029
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Binding affinity to Pseudomonas aeruginosa heme oxygenase
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Pseudomonas aeruginosa |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Inhibition of the bacterial heme oxygenases from Pseudomonas aeruginosa and Neisseria meningitidis: novel antimicrobial targets.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 8 | 4.65 | 5.21 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL230638 | — | — | 1 | 5.21 |
| CHEMBL395101 | — | — | 1 | 4.80 |
| CHEMBL425837 | — | — | 1 | 4.80 |
| CHEMBL395102 | — | — | 1 | 4.70 |
| CHEMBL244625 | — | — | 1 | 4.52 |
| CHEMBL230431 | — | — | 1 | 4.35 |
| CHEMBL1996376 | — | — | 1 | 4.14 |
| CHEMBL396483 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL230638 | — | Kd | = | 6100.0 | nM | 5.21 |
| CHEMBL395101 | — | Kd | = | 15900.0 | nM | 4.80 |
| CHEMBL425837 | — | Kd | = | 15800.0 | nM | 4.80 |
| CHEMBL395102 | — | Kd | = | 20100.0 | nM | 4.70 |
| CHEMBL244625 | — | Kd | = | 30000.0 | nM | 4.52 |
| CHEMBL230431 | — | Kd | = | 44700.0 | nM | 4.35 |
| CHEMBL1996376 | — | Kd | = | 72800.0 | nM | 4.14 |
| CHEMBL396483 | — | Kd | = | 187300.0 | nM | - |