Assay Detail
Binding
CHEMBL895117
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Inhibition of Src
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Target
Proto-oncogene tyrosine-protein kinase Src (CHEMBL267) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Synthesis and biological activities of new checkpoint kinase 1 inhibitors structurally related to granulatimide.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.87 | 6.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL240747 | GRANULATIMIDE | — | 1 | 6.46 |
| CHEMBL397022 | — | — | 1 | 5.27 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL240747 | GRANULATIMIDE | IC50 | = | 350.0 | nM | 6.46 |
| CHEMBL397022 | — | IC50 | = | 5400.0 | nM | 5.27 |