Assay Detail
Binding
CHEMBL895212
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Inhibition of wild type HIV YU2 gp120 to CD4 binding
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Human immunodeficiency virus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Structure-activity relationships in the binding of chemically derivatized CD4 to gp120 from human immunodeficiency virus.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.14 | 7.48 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL276727 | IODOACETAMIDE | — | 1 | 7.48 |
| CHEMBL8211 | N-ETHYLMALEIMIDE | — | 1 | 5.49 |
| CHEMBL395814 | — | — | 1 | 5.45 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL276727 | IODOACETAMIDE | IC50 | = | 33.3 | nM | 7.48 |
| CHEMBL8211 | N-ETHYLMALEIMIDE | IC50 | = | 3220.0 | nM | 5.49 |
| CHEMBL395814 | — | IC50 | = | 3580.0 | nM | 5.45 |