Assay Detail
Binding
CHEMBL895323
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Binding affinity to beta amyloid protein 1-40 by fluorescence titration
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Polyfluorinated bis-styrylbenzene beta-amyloid plaque binding ligands.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 9 | 7.74 | 10.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL395776 | — | — | 1 | 10.52 |
| CHEMBL242853 | — | — | 1 | 8.03 |
| CHEMBL243076 | — | — | 1 | 8.02 |
| CHEMBL230329 | — | — | 1 | 8.00 |
| CHEMBL188635 | — | — | 1 | 7.96 |
| CHEMBL438116 | — | — | 1 | 7.80 |
| CHEMBL425822 | — | — | 1 | 7.58 |
| CHEMBL224392 | THIOFLAVIN T | — | 1 | 6.25 |
| CHEMBL397951 | — | — | 1 | 5.47 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL395776 | — | Kd | = | 0.03 | nM | 10.52 |
| CHEMBL242853 | — | Kd | = | 9.4 | nM | 8.03 |
| CHEMBL243076 | — | Kd | = | 9.5 | nM | 8.02 |
| CHEMBL230329 | — | Kd | = | 10.0 | nM | 8.00 |
| CHEMBL188635 | — | Kd | = | 11.0 | nM | 7.96 |
| CHEMBL438116 | — | Kd | = | 16.0 | nM | 7.80 |
| CHEMBL425822 | — | Kd | = | 26.0 | nM | 7.58 |
| CHEMBL224392 | THIOFLAVIN T | Kd | = | 560.0 | nM | 6.25 |
| CHEMBL397951 | — | Kd | = | 3400.0 | nM | 5.47 |