Assay Detail
Binding
CHEMBL895705
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Binding affinity to YFP fused 5HT4 receptor expressed in CHO cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Synthesis of specific bivalent probes that functionally interact with 5-HT(4) receptor dimers.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 8.54 | 9.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL33884 | — | — | 1 | 9.15 |
| CHEMBL286136 | — | — | 1 | 8.46 |
| CHEMBL2113289 | — | — | 1 | 8.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL33884 | — | Ki | = | 0.7 | nM | 9.15 |
| CHEMBL286136 | — | Ki | = | 3.5 | nM | 8.46 |
| CHEMBL2113289 | — | Ki | = | 10.0 | nM | 8.00 |