Assay Detail
Binding
CHEMBL895871
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Inhibition of Bacillus anthracis DHFR
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bacillus anthracis |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Crystal structure of the anthrax drug target, Bacillus anthracis dihydrofolate reductase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.82 | 7.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL437567 | — | — | 1 | 7.82 |
| CHEMBL56190 | — | — | 1 | - |
| CHEMBL242199 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL437567 | — | IC50 | = | 15.0 | nM | 7.82 |
| CHEMBL56190 | — | IC50 | = | 104200.0 | nM | - |
| CHEMBL242199 | — | IC50 | - | — | - |