Assay Detail
Binding
CHEMBL896543
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Binding affinity to mouse CB2 receptor
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
2-Arylimino-5,6-dihydro-4H-1,3-thiazines as a new class of cannabinoid receptor agonists. Part 2: orally bioavailable compounds.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 8.53 | 9.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL232116 | — | — | 1 | 9.15 |
| CHEMBL443842 | — | — | 1 | 8.92 |
| CHEMBL232328 | — | — | 1 | 8.40 |
| CHEMBL232129 | — | — | 1 | 8.15 |
| CHEMBL465 | DRONABINOL | 4.0 | 1 | 8.04 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL232116 | — | Ki | = | 0.7 | nM | 9.15 |
| CHEMBL443842 | — | Ki | = | 1.2 | nM | 8.92 |
| CHEMBL232328 | — | Ki | = | 4.0 | nM | 8.40 |
| CHEMBL232129 | — | Ki | = | 7.0 | nM | 8.15 |
| CHEMBL465 | DRONABINOL | Ki | = | 9.2 | nM | 8.04 |