Assay Detail
Functional
CHEMBL896739
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Cytotoxicity against mouse L1210 cells by MTT assay
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | L1210 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and bioevaluation of N-(arylalkyl)-homospermidine conjugates.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 11 | 4.87 | 5.32 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL540552 | — | — | 1 | 5.32 |
| CHEMBL540336 | — | — | 1 | 5.09 |
| CHEMBL536076 | — | — | 1 | 5.00 |
| CHEMBL536297 | — | — | 1 | 4.83 |
| CHEMBL536524 | — | — | 1 | 4.82 |
| CHEMBL557367 | — | — | 1 | 4.82 |
| CHEMBL536075 | — | — | 1 | 4.77 |
| CHEMBL536525 | — | — | 1 | 4.69 |
| CHEMBL536523 | — | — | 1 | 4.45 |
| CHEMBL536299 | — | — | 1 | - |
| CHEMBL540379 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL540552 | — | IC50 | = | 4800.0 | nM | 5.32 |
| CHEMBL540336 | — | IC50 | = | 8040.0 | nM | 5.09 |
| CHEMBL536076 | — | IC50 | = | 9980.0 | nM | 5.00 |
| CHEMBL536297 | — | IC50 | = | 14770.0 | nM | 4.83 |
| CHEMBL536524 | — | IC50 | = | 15090.0 | nM | 4.82 |
| CHEMBL557367 | — | IC50 | = | 15060.0 | nM | 4.82 |
| CHEMBL536075 | — | IC50 | = | 16940.0 | nM | 4.77 |
| CHEMBL536525 | — | IC50 | = | 20260.0 | nM | 4.69 |
| CHEMBL536523 | — | IC50 | = | 35770.0 | nM | 4.45 |
| CHEMBL536299 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL540379 | — | IC50 | > | 50000.0 | nM | - |