Assay Detail
Functional
CHEMBL896742
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Cytotoxicity against mouse B16 cells by MTT assay
13
Total Activities
13
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | B16 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and bioevaluation of N-(arylalkyl)-homospermidine conjugates.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 13 | 5.46 | 6.51 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL540552 | — | — | 1 | 6.51 |
| CHEMBL536076 | — | — | 1 | 5.91 |
| CHEMBL536075 | — | — | 1 | 5.78 |
| CHEMBL540336 | — | — | 1 | 5.63 |
| CHEMBL536523 | — | — | 1 | 5.54 |
| CHEMBL557367 | — | — | 1 | 5.31 |
| CHEMBL536299 | — | — | 1 | 5.26 |
| CHEMBL540379 | — | — | 1 | 5.22 |
| CHEMBL536297 | — | — | 1 | 5.16 |
| CHEMBL237978 | — | — | 1 | 4.96 |
| CHEMBL233423 | — | — | 1 | 4.82 |
| CHEMBL536525 | — | — | 1 | - |
| CHEMBL536524 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL540552 | — | IC50 | = | 310.0 | nM | 6.51 |
| CHEMBL536076 | — | IC50 | = | 1220.0 | nM | 5.91 |
| CHEMBL536075 | — | IC50 | = | 1660.0 | nM | 5.78 |
| CHEMBL540336 | — | IC50 | = | 2330.0 | nM | 5.63 |
| CHEMBL536523 | — | IC50 | = | 2890.0 | nM | 5.54 |
| CHEMBL557367 | — | IC50 | = | 4880.0 | nM | 5.31 |
| CHEMBL536299 | — | IC50 | = | 5460.0 | nM | 5.26 |
| CHEMBL540379 | — | IC50 | = | 6070.0 | nM | 5.22 |
| CHEMBL536297 | — | IC50 | = | 6960.0 | nM | 5.16 |
| CHEMBL237978 | — | IC50 | = | 10840.0 | nM | 4.96 |
| CHEMBL233423 | — | IC50 | = | 15010.0 | nM | 4.82 |
| CHEMBL536525 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL536524 | — | IC50 | > | 50000.0 | nM | - |