Assay Detail
Binding
CHEMBL896779
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Inhibition of human recombinant placental SAH
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Design, synthesis, and molecular modeling studies of 5'-deoxy-5'-ureidoadenosine: 5'-ureido group as multiple hydrogen bonding donor in the active site of S-adenosylhomocysteine hydrolase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.59 | 5.12 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL231952 | — | — | 1 | 5.12 |
| CHEMBL232751 | — | — | 1 | 4.54 |
| CHEMBL302376 | — | — | 1 | 4.12 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL231952 | — | IC50 | = | 7530.0 | nM | 5.12 |
| CHEMBL232751 | — | IC50 | = | 28940.0 | nM | 4.54 |
| CHEMBL302376 | — | IC50 | = | 75020.0 | nM | 4.12 |