Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL896789

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibition of cholesterol synthesis in HepG2 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HepG2
Confidence 1 — Organism
Curated By Autocuration

Target

HepG2 (CHEMBL395)
Type CELL-LINE
Organism Homo sapiens

Publication

Aminopyrrolidineamide inhibitors of site-1 protease.
Hay BA, Abrams B, Zumbrunn AY, Valentine JJ, Warren LC, Petras SF, Shelly LD, Xia A, Varghese AH, Hawkins JL, Van Camp JA, Robbins MD, Landschulz K, Harwood HJ.
Bioorg Med Chem Lett (2007) 17 : 4411 -4414
PubMed 17583500 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 6.22 6.22

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL233611 1 6.22

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL233611 EC50 = 600.0 nM 6.22