Assay Detail
Functional
CHEMBL896823
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at human LXRalpha receptor after 1 hr by HTRF cofactor recruitment assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
2-Aryl-N-acyl indole derivatives as liver X receptor (LXR) agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 7 | 6.30 | 7.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL62136 | T091317 | — | 1 | 7.40 |
| CHEMBL392996 | — | — | 1 | 6.66 |
| CHEMBL59030 | — | — | 1 | 6.43 |
| CHEMBL393966 | — | — | 1 | 5.96 |
| CHEMBL397612 | — | — | 1 | 5.94 |
| CHEMBL397564 | — | — | 1 | 5.92 |
| CHEMBL233369 | — | — | 1 | 5.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL62136 | T091317 | EC50 | = | 40.0 | nM | 7.40 |
| CHEMBL392996 | — | EC50 | = | 220.0 | nM | 6.66 |
| CHEMBL59030 | — | EC50 | = | 367.0 | nM | 6.43 |
| CHEMBL393966 | — | EC50 | = | 1110.0 | nM | 5.96 |
| CHEMBL397612 | — | EC50 | = | 1150.0 | nM | 5.94 |
| CHEMBL397564 | — | EC50 | = | 1190.0 | nM | 5.92 |
| CHEMBL233369 | — | EC50 | = | 1500.0 | nM | 5.82 |