Assay Detail
Functional
CHEMBL896884
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Cytotoxicity against human PC3 cells by MTS assay after 24 hrs
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | PC-3 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
An investigation into the cytotoxicity and mode of action of some novel N-alkyl-substituted isatins.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 5.47 | 5.93 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL396549 | — | — | 1 | 5.93 |
| CHEMBL244900 | — | — | 1 | 5.66 |
| CHEMBL244711 | — | — | 1 | 5.51 |
| CHEMBL244712 | — | — | 1 | 5.47 |
| CHEMBL244901 | — | — | 1 | 5.46 |
| CHEMBL395485 | — | — | 1 | 5.46 |
| CHEMBL244322 | — | — | 1 | 5.34 |
| CHEMBL428921 | — | — | 1 | 4.96 |
| CHEMBL244899 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL396549 | — | IC50 | = | 1170.0 | nM | 5.93 |
| CHEMBL244900 | — | IC50 | = | 2170.0 | nM | 5.66 |
| CHEMBL244711 | — | IC50 | = | 3060.0 | nM | 5.51 |
| CHEMBL244712 | — | IC50 | = | 3420.0 | nM | 5.47 |
| CHEMBL244901 | — | IC50 | = | 3440.0 | nM | 5.46 |
| CHEMBL395485 | — | IC50 | = | 3500.0 | nM | 5.46 |
| CHEMBL244322 | — | IC50 | = | 4570.0 | nM | 5.34 |
| CHEMBL428921 | — | IC50 | = | 10900.0 | nM | 4.96 |
| CHEMBL244899 | — | IC50 | - | — | - |