Assay Detail
Binding
CHEMBL897017
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Inhibition of CDK1
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
3-Hydroxychromones as cyclin-dependent kinase inhibitors: synthesis and biological evaluation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 7.07 | 7.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL392776 | — | — | 1 | 7.72 |
| CHEMBL392775 | — | — | 1 | 7.48 |
| CHEMBL233153 | — | — | 1 | 7.20 |
| CHEMBL232557 | — | — | 1 | 6.89 |
| CHEMBL233152 | — | — | 1 | 6.80 |
| CHEMBL232749 | — | — | 1 | 6.35 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL392776 | — | IC50 | = | 19.0 | nM | 7.72 |
| CHEMBL392775 | — | IC50 | = | 33.0 | nM | 7.48 |
| CHEMBL233153 | — | IC50 | = | 63.0 | nM | 7.20 |
| CHEMBL232557 | — | IC50 | = | 130.0 | nM | 6.89 |
| CHEMBL233152 | — | IC50 | = | 160.0 | nM | 6.80 |
| CHEMBL232749 | — | IC50 | = | 450.0 | nM | 6.35 |