Assay Detail
Binding
CHEMBL897463
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Inhibition of bacterial glucosamine-6-phosphate synthase by colorimetric morgan-elson assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Discovering new inhibitors of bacterial glucosamine-6P synthase (GlmS) by docking simulations.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.15 | 4.25 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL396380 | — | — | 1 | 4.25 |
| CHEMBL428194 | — | — | 1 | 4.16 |
| CHEMBL233833 | — | — | 1 | 4.16 |
| CHEMBL391936 | — | — | 1 | 4.16 |
| CHEMBL232801 | AMITROLE | — | 1 | 4.00 |
| CHEMBL234658 | AAPTAMINE | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL396380 | — | IC50 | = | 56000.0 | nM | 4.25 |
| CHEMBL428194 | — | IC50 | = | 70000.0 | nM | 4.16 |
| CHEMBL233833 | — | IC50 | = | 70000.0 | nM | 4.16 |
| CHEMBL391936 | — | IC50 | = | 70000.0 | nM | 4.16 |
| CHEMBL232801 | AMITROLE | IC50 | = | 100000.0 | nM | 4.00 |
| CHEMBL234658 | AAPTAMINE | IC50 | = | 120000.0 | nM | - |