Assay Detail
Binding
CHEMBL897806
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to human NET
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Target
Sodium-dependent noradrenaline transporter (CHEMBL222) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Benzylamine histamine H(3) antagonists and serotonin reuptake inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 6.70 | 7.02 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL391074 | — | — | 1 | 7.02 |
| CHEMBL391947 | — | — | 1 | 6.62 |
| CHEMBL237512 | — | — | 1 | 6.60 |
| CHEMBL236046 | — | — | 1 | 6.54 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL391074 | — | Ki | = | 96.0 | nM | 7.02 |
| CHEMBL391947 | — | Ki | = | 240.0 | nM | 6.62 |
| CHEMBL237512 | — | Ki | = | 250.0 | nM | 6.60 |
| CHEMBL236046 | — | Ki | = | 290.0 | nM | 6.54 |