Assay Detail
Binding
CHEMBL898004
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Inhibition of HDAC in HeLa cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HeLa |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Pomiferin, histone deacetylase inhibitor isolated from the fruits of Maclura pomifera.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.00 | 6.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL98 | VORINOSTAT | 4.0 | 1 | 6.85 |
| CHEMBL393136 | POMIFERIN | — | 1 | 5.98 |
| CHEMBL238188 | OSAJIN | — | 1 | 5.18 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL98 | VORINOSTAT | IC50 | = | 140.0 | nM | 6.85 |
| CHEMBL393136 | POMIFERIN | IC50 | = | 1050.0 | nM | 5.98 |
| CHEMBL238188 | OSAJIN | IC50 | = | 6530.0 | nM | 5.18 |