Assay Detail
Binding
CHEMBL898082
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Inhibition of human tPA
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
SAR and X-ray structures of enantiopure 1,2-cis-(1R,2S)-cyclopentyldiamine and cyclohexyldiamine derivatives as inhibitors of coagulation Factor Xa.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 5.26 | 5.26 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL398380 | — | — | 1 | 5.26 |
| CHEMBL233992 | — | — | 1 | - |
| CHEMBL399593 | — | — | 1 | - |
| CHEMBL450578 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL398380 | — | Ki | = | 5502.0 | nM | 5.26 |
| CHEMBL233992 | — | Ki | > | 20000.0 | nM | - |
| CHEMBL399593 | — | Ki | > | 20000.0 | nM | - |
| CHEMBL450578 | — | Ki | > | 20000.0 | nM | - |