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Assay Detail

CHEMBL898307

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Yersinia Tyrosine-protein phosphatase yopH
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Yersinia sp.
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

5-Arylidene-2,4-thiazolidinediones as inhibitors of protein tyrosine phosphatases.
Maccari R, Paoli P, Ottanà R, Jacomelli M, Ciurleo R, Manao G, Steindl T, Langer T, Vigorita MG, Camici G.
Bioorg Med Chem (2007) 15 : 5137 -5149
PubMed 17543532 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 6.26 6.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL235595 1 6.52
CHEMBL393606 1 6.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL235595 IC50 = 300.0 nM 6.52
CHEMBL393606 IC50 = 1000.0 nM 6.00