Assay Detail
Binding
CHEMBL899403
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Inhibition of YOP after 10 mins
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
2-O-carboxymethylpyrogallol derivatives as PTP1B inhibitors with antihyperglycemic activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.76 | 5.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL238138 | — | — | 1 | 5.22 |
| CHEMBL236636 | — | — | 1 | 4.89 |
| CHEMBL238137 | — | — | 1 | 4.82 |
| CHEMBL237915 | — | — | 1 | 4.68 |
| CHEMBL236216 | — | — | 1 | 4.48 |
| CHEMBL393866 | — | — | 1 | 4.47 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL238138 | — | IC50 | = | 6000.0 | nM | 5.22 |
| CHEMBL236636 | — | IC50 | = | 13000.0 | nM | 4.89 |
| CHEMBL238137 | — | IC50 | = | 15000.0 | nM | 4.82 |
| CHEMBL237915 | — | IC50 | = | 21000.0 | nM | 4.68 |
| CHEMBL236216 | — | IC50 | = | 33000.0 | nM | 4.48 |
| CHEMBL393866 | — | IC50 | = | 34000.0 | nM | 4.47 |