Assay Detail
Binding
CHEMBL899761
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Binding affinity at human MC5R
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Pyrrolidinones as potent functional antagonists of the human melanocortin-4 receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 6.08 | 6.28 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL236521 | — | — | 1 | 6.28 |
| CHEMBL393576 | — | — | 1 | 6.07 |
| CHEMBL397580 | — | — | 1 | 5.89 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL236521 | — | Ki | = | 520.0 | nM | 6.28 |
| CHEMBL393576 | — | Ki | = | 850.0 | nM | 6.07 |
| CHEMBL397580 | — | Ki | = | 1300.0 | nM | 5.89 |