Assay Detail
Binding
CHEMBL900718
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Inhibition of human recombinant MAOA expressed in Pichia pastoris
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Structures of human monoamine oxidase B complexes with selective noncovalent inhibitors: safinamide and coumarin analogs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 4.88 | 4.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL239508 | — | — | 1 | 4.96 |
| CHEMBL239507 | — | — | 1 | 4.80 |
| CHEMBL396778 | SAFINAMIDE | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL239508 | — | Ki | = | 11000.0 | nM | 4.96 |
| CHEMBL239507 | — | Ki | = | 15700.0 | nM | 4.80 |
| CHEMBL396778 | SAFINAMIDE | Ki | = | 365000.0 | nM | - |