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Assay Detail

CHEMBL901234

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of bovine pancreatic carboxypeptidase A
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Bos taurus
Confidence 9 — Direct single protein target
Curated By Intermediate

Target

Carboxypeptidase A1 (CHEMBL3481)
Type SINGLE PROTEIN
Organism Bos taurus

Publication

Discovery of potent & selective inhibitors of activated thrombin-activatable fibrinolysis inhibitor for the treatment of thrombosis.
Bunnage ME, Blagg J, Steele J, Owen DR, Allerton C, McElroy AB, Miller D, Ringer T, Butcher K, Beaumont K, Evans K, Gray AJ, Holland SJ, Feeder N, Moore RS, Brown DG.
J Med Chem (2007) 50 : 6095 -6103
PubMed 17990866 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.96 7.96

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL58957 1 7.96

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL58957 Ki = 11.0 nM 7.96