Assay Detail
Functional
CHEMBL901524
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Cytotoxicity against human MCF7 cells assessed as cell viability by tryptan blue staining method
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Stereoselective synthesis and cytotoxicity of a cancer chemopreventive naphthoquinone from Tabebuia avellanedae.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 5.40 | 6.02 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL105 | MITOMYCIN | 4.0 | 1 | 6.02 |
| CHEMBL392591 | — | — | 1 | 5.46 |
| CHEMBL392384 | — | — | 1 | 5.07 |
| CHEMBL239211 | — | — | 1 | 5.03 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL105 | MITOMYCIN | EC50 | = | 960.0 | nM | 6.02 |
| CHEMBL392591 | — | EC50 | = | 3500.0 | nM | 5.46 |
| CHEMBL392384 | — | EC50 | = | 8500.0 | nM | 5.07 |
| CHEMBL239211 | — | EC50 | = | 9300.0 | nM | 5.03 |