Assay Detail
Functional
CHEMBL901533
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Inhibition of TPA-induced EBV-EA activation in Raji cells
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human gammaherpesvirus 4 |
| Cell Type | Raji |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Stereoselective synthesis and cytotoxicity of a cancer chemopreventive naphthoquinone from Tabebuia avellanedae.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.45 | 4.48 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL392591 | — | — | 1 | 4.48 |
| CHEMBL392384 | — | — | 1 | 4.46 |
| CHEMBL239211 | — | — | 1 | 4.41 |
| CHEMBL15193 | LAPACHOL | — | 1 | - |
| CHEMBL15192 | LAPACHONE | 2.0 | 1 | - |
| CHEMBL140 | CURCUMIN | 3.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL392591 | — | IC50 | = | 33200.0 | nM | 4.48 |
| CHEMBL392384 | — | IC50 | = | 34900.0 | nM | 4.46 |
| CHEMBL239211 | — | IC50 | = | 38900.0 | nM | 4.41 |
| CHEMBL15193 | LAPACHOL | IC50 | = | 311400.0 | nM | - |
| CHEMBL15192 | LAPACHONE | IC50 | = | 210300.0 | nM | - |
| CHEMBL140 | CURCUMIN | IC50 | = | 345000.0 | nM | - |