Assay Detail
Binding
CHEMBL902040
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Inhibition of RGGT
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthesis and biological evaluation of alpha-halogenated bisphosphonate and phosphonocarboxylate analogues of risedronate.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.68 | 4.79 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL240772 | — | — | 1 | 4.79 |
| CHEMBL240771 | — | — | 1 | 4.79 |
| CHEMBL240775 | — | — | 1 | 4.75 |
| CHEMBL397829 | — | — | 1 | 4.62 |
| CHEMBL240776 | — | — | 1 | 4.45 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL240772 | — | IC50 | = | 16400.0 | nM | 4.79 |
| CHEMBL240771 | — | IC50 | = | 16300.0 | nM | 4.79 |
| CHEMBL240775 | — | IC50 | = | 17700.0 | nM | 4.75 |
| CHEMBL397829 | — | IC50 | = | 24100.0 | nM | 4.62 |
| CHEMBL240776 | — | IC50 | = | 35300.0 | nM | 4.45 |