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Assay Detail

CHEMBL903835

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Growth inhibition of human T24 cells by neutral red assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type T-24
Confidence 1 — Organism
Curated By Autocuration

Target

T-24 (CHEMBL614774)
Type CELL-LINE
Organism Homo sapiens

Publication

Biological profile of new apoptotic agents based on 2,4-pyrido[2,3-d]pyrimidine derivatives.
Cordeu L, Cubedo E, Bandrés E, Rebollo A, Sáenz X, Chozas H, Victoria Domínguez M, Echeverría M, Mendivil B, Sanmartin C, Palop JA, Font M, García-Foncillas J.
Bioorg Med Chem (2007) 15 : 1659 -1669
PubMed 17204425 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 6.76 8.22

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL65 CAMPTOTHECIN -1.0 1 8.22
CHEMBL390090 1 5.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL65 CAMPTOTHECIN IC50 = 6.0 nM 8.22
CHEMBL390090 IC50 = 5000.0 nM 5.30