Assay Detail
Functional
CHEMBL904236
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Growth inhibition in HepG2 cells after 7 days
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HepG2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Stabilization of G-quadruplex DNA and down-regulation of oncogene c-myc by quindoline derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.21 | 6.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL222252 | — | — | 1 | 6.52 |
| CHEMBL376497 | — | — | 1 | 5.89 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL222252 | — | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL376497 | — | IC50 | = | 1300.0 | nM | 5.89 |