Assay Detail
Binding
CHEMBL904428
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Inhibition of human trypsin by chromogenic assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Design, synthesis and biological activity of selective and orally available TF/FVIIa complex inhibitors containing non-amidine P1 ligands.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.32 | 5.32 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL224485 | — | — | 1 | 5.32 |
| CHEMBL375051 | — | — | 1 | 5.32 |
| CHEMBL376806 | — | — | 1 | - |
| CHEMBL388161 | — | — | 1 | - |
| CHEMBL426187 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL224485 | — | IC50 | = | 4800.0 | nM | 5.32 |
| CHEMBL375051 | — | IC50 | = | 4800.0 | nM | 5.32 |
| CHEMBL376806 | — | IC50 | > | 200000.0 | nM | - |
| CHEMBL388161 | — | IC50 | > | 200000.0 | nM | - |
| CHEMBL426187 | — | IC50 | > | 200000.0 | nM | - |