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Assay Detail

CHEMBL904588

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of horseradish peroxidase catalytic activity by luminol-enhanced chemiluminescence assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Armoracia rusticana
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Inhibition of horseradish peroxidase catalytic activity by new 3-phenylcoumarin derivatives: synthesis and structure-activity relationships.
Kabeya LM, de Marchi AA, Kanashiro A, Lopes NP, da Silva CH, Pupo MT, Lucisano-Valim YM.
Bioorg Med Chem (2007) 15 : 1516 -1524
PubMed 17112729 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 5 5.22 5.92

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL388343 1 5.92
CHEMBL228221 1 5.55
CHEMBL426200 1 5.47
CHEMBL227562 1 4.61
CHEMBL67599 1 4.55

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL388343 IC50 = 1200.0 nM 5.92
CHEMBL228221 IC50 = 2800.0 nM 5.55
CHEMBL426200 IC50 = 3400.0 nM 5.47
CHEMBL227562 IC50 = 24600.0 nM 4.61
CHEMBL67599 IC50 = 28200.0 nM 4.55