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Assay Detail

CHEMBL904774

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Functional
Growth inhibition of chloroquine-sensitive Plasmodium falciparum FCK2 in human erythrocytes after 96 hrs
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Plasmodium falciparum
Confidence 1 — Organism
Curated By Intermediate

Target

Plasmodium falciparum (CHEMBL364)
Type ORGANISM
Organism Plasmodium falciparum

Publication

Discovery of a rhodanine class of compounds as inhibitors of Plasmodium falciparum enoyl-acyl carrier protein reductase.
Kumar G, Parasuraman P, Sharma SK, Banerjee T, Karmodiya K, Surolia N, Surolia A.
J Med Chem (2007) 50 : 2665 -2675
PubMed 17477517 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
MIC 1 - -
IC50 1 6.12 6.12

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL228097 2 6.12

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL228097 IC50 = 750.0 nM 6.12
CHEMBL228097 MIC = 2500.0 nM -