Assay Detail
Binding
CHEMBL904794
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Inhibition of CDK2
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Pyrrolopyridine inhibitors of mitogen-activated protein kinase-activated protein kinase 2 (MK-2).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.35 | 6.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL225519 | — | — | 1 | 6.77 |
| CHEMBL388566 | — | — | 1 | 4.75 |
| CHEMBL226471 | — | — | 1 | 4.52 |
| CHEMBL226403 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL225519 | — | IC50 | = | 170.0 | nM | 6.77 |
| CHEMBL388566 | — | IC50 | = | 18000.0 | nM | 4.75 |
| CHEMBL226471 | — | IC50 | = | 30000.0 | nM | 4.52 |
| CHEMBL226403 | — | IC50 | > | 200000.0 | nM | - |