Assay Detail
Binding
CHEMBL906615
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Saccharomyces cerevisiae cytoplasmic leucyl-tRNA synthetase after 2 mins
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Saccharomyces cerevisiae |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Leucine--tRNA ligase, cytoplasmic (CHEMBL1075253) ↗| Type | SINGLE PROTEIN |
| Organism | Saccharomyces cerevisiae S288c |
Publication
An antifungal agent inhibits an aminoacyl-tRNA synthetase by trapping tRNA in the editing site.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 4.50 | 4.50 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL443052 | TAVABOROLE | 4.0 | 1 | 4.50 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL443052 | TAVABOROLE | Ki | = | 31400.0 | nM | 4.50 |