Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL906657

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of recombinant deoxyhypusine synthase in Plasmodium falciparum NF54
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Plasmodium falciparum NF54
Confidence 8 — Homologous single protein target
Curated By Intermediate

Target

Deoxyhypusine synthase (CHEMBL6074)
Type SINGLE PROTEIN
Organism Plasmodium falciparum

Publication

Modification of eukaryotic initiation factor 5A from Plasmodium vivax by a truncated deoxyhypusine synthase from Plasmodium falciparum: An enzyme with dual enzymatic properties.
Kaiser A, Hammels I, Gottwald A, Nassar M, Zaghloul MS, Motaal BA, Hauber J, Hoerauf A.
Bioorg Med Chem (2007) 15 : 6200 -6207
PubMed 17591443 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 5.65 7.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL229457 1 7.00
CHEMBL28242 1 4.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL229457 Ki = 100.0 nM 7.00
CHEMBL28242 Ki = 50000.0 nM 4.30