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Assay Detail

CHEMBL906744

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Functional
Superoxide radical scavenging activity by NBT reduction assay
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

2-Styrylchromones: novel strong scavengers of reactive oxygen and nitrogen species.
Gomes A, Fernandes E, Silva AM, Santos CM, Pinto DC, Cavaleiro JA, Lima JL.
Bioorg Med Chem (2007) 15 : 6027 -6036
PubMed 17624791 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 9 4.26 4.61

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL7983 PROPYL GALLATE 1.0 1 4.61
CHEMBL50 QUERCETIN 3.0 1 4.33
CHEMBL228622 1 4.31
CHEMBL374371 1 4.29
CHEMBL151 LUTEOLIN 2.0 1 4.23
CHEMBL390582 1 4.18
CHEMBL374372 1 4.15
CHEMBL228673 1 4.11
CHEMBL228623 1 4.09

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL7983 PROPYL GALLATE IC50 = 24600.0 nM 4.61
CHEMBL50 QUERCETIN IC50 = 47300.0 nM 4.33
CHEMBL228622 IC50 = 48900.0 nM 4.31
CHEMBL374371 IC50 = 51000.0 nM 4.29
CHEMBL151 LUTEOLIN IC50 = 58500.0 nM 4.23
CHEMBL390582 IC50 = 66200.0 nM 4.18
CHEMBL374372 IC50 = 71300.0 nM 4.15
CHEMBL228673 IC50 = 77700.0 nM 4.11
CHEMBL228623 IC50 = 80400.0 nM 4.09