Assay Detail
Functional
CHEMBL908003
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human CA46 cell line
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | CA46 |
| Confidence | 1 — Organism |
| Curated By | Expert |
Publication
Total synthesis and biological evaluation of ustiloxin natural products and two analogs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.56 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL39541 | DOLASTATIN-10 | 2.0 | 1 | 7.52 |
| CHEMBL212074 | USTILOXIN A | — | 1 | 5.60 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL39541 | DOLASTATIN-10 | IC50 | = | 30.0 | nM | 7.52 |
| CHEMBL212074 | USTILOXIN A | IC50 | = | 2500.0 | nM | 5.60 |