Assay Detail
Binding
CHEMBL908012
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Inhibition of bovine F10a
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bos taurus |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Diphenyl phosphonate inhibitors for the urokinase-type plasminogen activator: optimization of the P4 position.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.19 | 4.48 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL214814 | — | — | 1 | 4.48 |
| CHEMBL386249 | — | — | 1 | 4.24 |
| CHEMBL311067 | — | — | 1 | 4.19 |
| CHEMBL385897 | — | — | 1 | 4.02 |
| CHEMBL386275 | — | — | 1 | 4.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL214814 | — | IC50 | = | 33000.0 | nM | 4.48 |
| CHEMBL386249 | — | IC50 | = | 58000.0 | nM | 4.24 |
| CHEMBL311067 | — | IC50 | = | 65000.0 | nM | 4.19 |
| CHEMBL385897 | — | IC50 | = | 96000.0 | nM | 4.02 |
| CHEMBL386275 | — | IC50 | = | 100000.0 | nM | 4.00 |