Assay Detail
Functional
CHEMBL908443
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Inhibition of bovine nasal cartilage degradation
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Bos taurus |
| Tissue | Nasal cartilage |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Potent, selective pyrimidinetrione-based inhibitors of MMP-13.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.40 | 7.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL222077 | — | — | 1 | 7.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL222077 | — | IC50 | = | 40.0 | nM | 7.40 |