Assay Detail
Functional
CHEMBL908678
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of replication in Huh-9-13 cells containing Wild type HCV replicons after 72 hrs
2
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Hepatitis C virus (HCV) NS5B nonnucleoside inhibitors specifically block single-stranded viral RNA synthesis catalyzed by HCV replication complexes in vitro.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Activity | 1 | - | - |
| EC50 | 1 | 6.05 | 6.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL176058 | — | — | 1 | 6.05 |
| CHEMBL353549 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL176058 | — | EC50 | = | 900.0 | nM | 6.05 |
| CHEMBL353549 | — | Activity | - | — | - |