Assay Detail
Binding
CHEMBL908769
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Inhibition of TK2
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
N1-substituted thymine derivatives as mitochondrial thymidine kinase (TK-2) inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 6.42 | 6.54 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL220459 | — | — | 1 | 6.54 |
| CHEMBL101135 | — | — | 1 | 6.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL220459 | — | Ki | = | 290.0 | nM | 6.54 |
| CHEMBL101135 | — | Ki | = | 500.0 | nM | 6.30 |