Assay Detail

CHEMBL909082

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Functional

Cytotoxicity against human H460 cell line

ChEMBL ↗

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Target

NCI-H460 (CHEMBL396) ↗

Open DB target context

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NCI-H460 (CHEMBL396) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target NCI-H460

CHEMBL396

Anchored from Assay target.

Protein identity NCI-H460

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	NCI-H460
Confidence	1 — Organism
Curated By	Expert

Target

NCI-H460 (CHEMBL396) ↗

Type	CELL-LINE
Organism	Homo sapiens

Publication

Cinnabaramides A-G: analogues of lactacystin and salinosporamide from a terrestrial streptomycete.

Stadler M, Bitzer J, Mayer-Bartschmid A, Müller H, Benet-Buchholz J, Gantner F, Tichy HV, Reinemer P, Bacon KB.
J Nat Prod (2007) 70 : 246 -252
PubMed 17249727 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	6.00	6.00

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL384099	CINNABARAMIDE A	—	1	6.00

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL384099	CINNABARAMIDE A	IC50	=	1000.0	nM	6.00