Assay Detail
Functional
CHEMBL909959
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at human LRH1 expressed in CV1 cells assessed as SHP reporter gene transactivation by luciferase assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | CV-1 |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Target
Nuclear receptor subfamily 5 group A member 2 (CHEMBL3544) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Identification of small molecule agonists of the orphan nuclear receptors liver receptor homolog-1 and steroidogenic factor-1.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 6.00 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL385911 | — | — | 1 | 6.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL385911 | — | EC50 | = | 1000.0 | nM | 6.00 |