Assay Detail
Binding
CHEMBL910700
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]AMPA from AMPA receptor in rat synaptic membrane
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Design, total synthesis, and biological evaluation of neodysiherbaine A derivative as potential probes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 6.82 | 6.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL221142 | DYSIHERBAINE | — | 1 | 6.82 |
| CHEMBL221868 | NEODYSIHERBAINE A | — | 1 | 6.82 |
| CHEMBL220852 | 10-HYDROXY-METHYL-NEODYSIHERBAINE A | — | 1 | 6.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL221142 | DYSIHERBAINE | Ki | = | 153.0 | nM | 6.82 |
| CHEMBL221868 | NEODYSIHERBAINE A | Ki | = | 151.0 | nM | 6.82 |
| CHEMBL220852 | 10-HYDROXY-METHYL-NEODYSIHERBAINE A | Ki | = | 153.0 | nM | 6.82 |